 | Calafiori | Muscle injury - Unknown return date | | | Mosquera | Ankle injury - Unknown return date |
| | Dowman | Ankle injury - Unknown return date |
 | Barkley | Knee injury - Expected back 07 Feb |
| | Kamara | Knee injury - Unknown return date |
| | Onana | Muscle injury - Expected back 25 Jan |
| | Alysson | Knock - Unknown return date |
 | Roberts | Achilles injury - Unknown return date |
| | Jordan | Hamstring injury - Unknown return date |
| | Cullen | Knee injury - Expected back 30 Sep |
| | Trésor | Ankle injury - Unknown return date |
| | Flemming | Knock - Expected back 24 Jan |
| | Amdouni | Knee injury - Expected back 25 Apr |
 | Dennis | Ankle injury - Unknown return date |
| | Kluivert | Knee injury - Expected back 09 May |
| | Adams | Knee injury - Expected back 21 Feb |
| | Enes Ünal | Muscle injury - Expected back 31 Jan |
| | Gannon-Doak | Hamstring injury - Unknown return date |
 | Milambo | Knee injury - Expected back 01 Jun |
| | Carvalho | Knee injury - Expected back 01 Jun |
| | Dasilva | Knee injury - Expected back 01 Feb |
 | Webster | Knee injury - Unknown return date |
| | Wieffer | Toe Injury - Unknown return date |
| | Tzimas | Knee injury - Expected back 01 Jun |
 | Colwill | Anterior cruciate ligament - Unknown return date |
| | Lavia | Thigh injury - Unknown return date |
 | Muñoz | Knee injury - Expected back 25 Jan |
| | Kporha | Back injury - Unknown return date |
| | Doucouré | Knee injury - Unknown return date |
| | Kamada | Hamstring injury - Expected back 21 Feb |
| | Nketiah | Hamstring injury - Unknown return date |
| | Cardines | Groin Injury - Expected back 25 Jan |
 | Dewsbury-Hall | Hamstring injury - Unknown return date |
| | Alcaraz | Knock - Unknown return date |
| | Iroegbunam | Knock - Unknown return date |
 | Tete | Hamstring injury - Unknown return date |
| | Muniz | Hamstring injury - Expected back 22 Feb |
 | Bijol | Hamstring injury - Expected back 21 Feb |
| | James | Hamstring injury - Expected back 31 Jan |
 | Bradley | Knee injury - Expected back 01 Jun |
| | Bajcetic | Hamstring injury - Unknown return date |
| | Danns | Hamstring injury - Unknown return date |
| | Isak | Ankle injury - Unknown return date |
| | Leoni | Knee injury - Expected back 01 Sep |
 | Gvardiol | Leg injury - Unknown return date |
| | Rúben | Hamstring injury - Expected back 11 Feb |
| | Stones | Thigh injury - Unknown return date |
| | Savinho | Thigh injury - Expected back 21 Feb |
| | Kovačić | Ankle injury - Unknown return date |
| | Bobb | Hamstring injury - Unknown return date |
 | De Ligt | Back injury - Unknown return date |
 | Schär | Ankle injury - Expected back 18 Apr |
| | Burn | Rib Injury - Expected back 25 Jan |
| | Livramento | Hamstring injury - Unknown return date |
| | Krafth | Knee injury - Unknown return date |
| | Osula | Ankle injury - Expected back 31 Jan |
 | Wood | Knee injury - Unknown return date |
| | John | Knee injury - Unknown return date |
 | Alese | Shoulder injury - Unknown return date |
| | Masuaku | Ankle injury - Expected back 22 Feb |
| | Traoré | Knee injury - Expected back 11 Feb |
 | Maddison | Anterior cruciate ligament - Unknown return date |
| | Kudus | Thigh injury - Expected back 11 Apr |
| | Kulusevski | Knee injury - Unknown return date |
| | Bentancur | Hamstring injury - Unknown return date |
| | Richarlison | Hamstring injury - Expected back 01 Mar |
 | Toti | Hamstring injury - Unknown return date |
| | Bellegarde | Hamstring injury - Expected back 24 Jan |
| | Chiwome | Knee injury - Unknown return date |
