 | G.Jesus | Knee injury - Unknown return date | | | Havertz | Hamstring injury - Expected back 01 Jun |
| | Martinelli | Hamstring injury - Expected back 01 Apr |
| | Saka | Hamstring injury - Expected back 01 Apr |
| | Tomiyasu | Knee injury - Expected back 01 Jun |
 | Enes Ünal | Knee injury - Unknown return date |
| | Senesi | Thigh injury - Expected back 01 Apr |
| | Smith | Muscle injury - Unknown return date |
 | Dasilva | Knee injury - Unknown return date |
| | Henry | Hamstring injury - Unknown return date |
| | Hickey | Hamstring injury - Unknown return date |
| | Thiago | Knee injury - Unknown return date |
| | Van den Berg | Knee injury - Unknown return date |
| | G.Nunes | Back injury - Unknown return date |
 | Dunk | Rib Injury - Unknown return date |
| | Igor | Hamstring injury - Expected back 01 Jun |
| | Milner | Hamstring injury - Unknown return date |
| | Steele | Shoulder injury - Unknown return date |
| | F.Kadıoğlu | Toe Injury - Unknown return date |
 | B.Badiashile | Muscle injury - Expected back 02 Apr |
| | Kellyman | Hamstring injury - Unknown return date |
| | Lavia | Muscle injury - Expected back 02 Apr |
| | Madueke | Hamstring injury - Expected back 02 Apr |
| | Marc Guiu | Hamstring injury - Expected back 02 Apr |
| | N.Jackson | Hamstring injury - Expected back 02 Apr |
 | C.Doucouré | Knee injury - Expected back 01 Jun |
| | Chadi Riad | Knee injury - Unknown return date |
| | Ward | Unknown - Unknown return date |
 | Broja | Ankle injury - Expected back 01 Apr |
| | Calvert-Lewin | Hamstring injury - Unknown return date |
| | Coleman | Calf injury - Unknown return date |
| | McNeil | Knee injury - Expected back 02 Apr |
| | Ndiaye | Knee injury - Unknown return date |
| | Mangala | Knee injury - Expected back 01 Jun |
 | Nelson | Hamstring injury - Expected back 25 May |
| | Tete | Knee injury - Expected back 01 Apr |
| | Wilson | Foot injury - Expected back 01 Apr |
 | Enciso | Knee injury - Unknown return date |
| | Burns | Knee injury - Expected back 01 Jun |
| | Walton | Groin Strain - Expected back 05 Apr |
| | Ogbene | Achilles injury - Expected back 01 Jun |
 | A.Fatawu | Knee injury - Expected back 01 Jun |
 | Bradley | Muscle injury - Unknown return date |
| | Gomez | Hamstring injury - Unknown return date |
| | Morton | Shoulder injury - Expected back 08 Mar |
 | Akanji | Muscle injury - Expected back 26 Apr |
| | Rodrigo | Knee injury - Expected back 01 Jun |
| | Stones | Thigh injury - Unknown return date |
 | Amad | Ankle injury - Unknown return date |
| | Bayindir | Knock - Unknown return date |
| | Evans | Muscle injury - Unknown return date |
| | Heaton | Knock - Unknown return date |
| | Mainoo | Knock - Unknown return date |
| | Martinez | Knee injury - Unknown return date |
| | Mount | Leg injury - Unknown return date |
| | Shaw | Knock - Unknown return date |
| | Collyer | Knock - Unknown return date |
 | Lascelles | Knee injury - Expected back 25 May |
 | Lallana | Hamstring injury - Unknown return date |
 | Dragusin | Knee injury - Expected back 01 Jun |
 | Antonio | Leg injury - Unknown return date |
| | L.Paquetá | Ankle injury - Expected back 10 Mar |
| | Summerville | Hamstring injury - Expected back 01 Apr |
| | Füllkrug | Hamstring injury - Unknown return date |
 | Chiwome | Knee injury - Expected back 01 Jun |
| | Gonzalez | Knee injury - Unknown return date |
| | Kalajdžić | Knee injury - Unknown return date |
| | Mosquera | Knee injury - Expected back 01 Jun |
| | R.Gomes | Pelvic - Unknown return date |
| | Agbadou | Muscle injury - Unknown return date |
