 | Buendia | Knee injury - Expected back 01 Jun | | | Kamara | Knee injury - Expected back 14 Sep |
| | Mings | Knee injury - Expected back 01 Jun |
| | J.Ramsey | Toe Injury - Expected back 01 Jun |
| | Fredericks | Calf injury - Unknown return date |
| | Mepham | Illness - Unknown return date |
| | Adams | Back injury - Unknown return date |
| | Sinisterra | Hamstring injury - Expected back 19 May |
| | Dasilva | Knee injury - Expected back 01 Jun |
| | Henry | Knee injury - Expected back 01 Jun |
| | Hickey | Hamstring injury - Expected back 01 Jun |
| | Mee | Ankle injury - Expected back 01 Jun |
| | Estupiñan | Ankle injury - Expected back 01 Jun |
| | Ferguson | Ankle injury - Expected back 01 Jun |
| | Lallana | Knock - Unknown return date |
| | Lamptey | Knock - Unknown return date |
| | March | Knee injury - Expected back 01 Jun |
| | Milner | Muscle injury - Unknown return date |
| | Mitoma | Back injury - Expected back 01 Jun |
| | Van Hecke | Hamstring injury - Unknown return date |
| | Hinshelwood | Foot injury - Expected back 01 Jun |
| | Al-Dakhil | Unknown - Expected back 01 Jun |
| | Beyer | Unknown - Expected back 01 Jun |
| | Redmond | Leg injury - Expected back 01 Jul |
| | Koleosho | Knee injury - Expected back 19 May |
| | A.Ramsey | Knee injury - Expected back 16 Nov |
| | Enzo | Groin Injury - Expected back 01 Jun |
| | W.Fofana | Knee injury - Expected back 01 Jun |
| | Lavia | Thigh injury - Expected back 01 Jun |
| | C.Doucouré | Achilles injury - Expected back 19 May |
| | Johnstone | Arm injury - Expected back 01 Jun |
| | Matheus França | Groin Injury - Unknown return date |
| | Dele | Groin Injury - Expected back 01 Jun |
| | Mykolenko | Ankle injury - Expected back 01 Jun |
| | Patterson | Hamstring injury - Expected back 01 Jun |
| | Matip | Knee injury - Expected back 19 May |
| | Thiago | Muscle injury - Unknown return date |
| | Doak | Knee injury - Unknown return date |
| | Nakamba | Knee injury - Expected back 01 Jun |
| | Bell | Hamstring injury - Expected back 01 Jun |
| | Lockyer | Illness - Unknown return date |
| | Kaboré | Ankle injury - Expected back 01 Jun |
| | Brown | Knee injury - Expected back 01 Jun |
| | Lindelof | Hamstring injury - Expected back 12 May |
| | Maguire | Muscle injury - Expected back 01 Jun |
| | Malacia | Knee injury - Unknown return date |
| | Martinez | Calf injury - Expected back 12 May |
| | R.Varane | Foot injury - Expected back 19 May |
| | Shaw | Muscle injury - Expected back 12 May |
| | Botman | Knee injury - Expected back 21 Dec |
| | Lascelles | Knee injury - Expected back 31 Dec |
| | Schär | Hamstring injury - Expected back 01 Jun |
| | Targett | Achilles injury - Expected back 01 Jun |
| | Willock | Achilles injury - Expected back 01 Jun |
| | Miley | Back injury - Expected back 01 Jun |
| | Baldock | Calf injury - Expected back 11 May |
| | Basham | Leg injury - Unknown return date |
| | Lowe | Ankle injury - Expected back 01 Jun |
| | McBurnie | Groin Injury - Expected back 01 Jun |
| | Norrington-Davies | Hamstring injury - Expected back 01 Jun |
| | Davies | Calf injury - Expected back 01 Jun |
| | Forster | Foot injury - Expected back 01 Jun |
| | Sessegnon | Hamstring injury - Expected back 01 Jun |
| | Udogie | Thigh injury - Expected back 01 Jun |
| | Solomon | Knee injury - Expected back 01 Jun |
| | Werner | Hamstring injury - Expected back 01 Jun |
| | Dawson | Groin Injury - Expected back 01 Jun |
| | Chiwome | Ankle injury - Expected back 01 Jun |
